Regularity of Cardiac Rhythm as a Marker of Sleepiness in Sleep Disordered Breathing
نویسندگان
چکیده
AIM The present study aimed to analyse the autonomic nervous system activity using heart rate variability (HRV) to detect sleep disordered breathing (SDB) patients with and without excessive daytime sleepiness (EDS) before sleep onset. METHODS Two groups of 20 patients with different levels of daytime sleepiness -sleepy group, SG; alert group, AG- were selected consecutively from a Maintenance of Wakefulness Test (MWT) and Multiple Sleep Latency Test (MSLT) research protocol. The first waking 3-min window of RR signal at the beginning of each nap test was considered for the analysis. HRV was measured with traditional linear measures and with time-frequency representations. Non-linear measures -correntropy, CORR; auto-mutual-information function, AMIF- were used to describe the regularity of the RR rhythm. Statistical analysis was performed with non-parametric tests. RESULTS Non-linear dynamic of the RR rhythm was more regular in the SG than in the AG during the first wakefulness period of MSLT, but not during MWT. AMIF (in high-frequency and in Total band) and CORR (in Total band) yielded sensitivity > 70%, specificity >75% and an area under ROC curve > 0.80 in classifying SG and AG patients. CONCLUSION The regularity of the RR rhythm measured at the beginning of the MSLT could be used to detect SDB patients with and without EDS before the appearance of sleep onset.
منابع مشابه
Prolonged Sleep Apnea in Two Patients with a History of Opium Abuse-A Case Report
Introduction: Obstructive sleep apnea (OSA) is a highly prevalent sleep-disordered breathing (SDB). Case Report: Two 53- and 51-year-old male cases with daytime sleepiness and opium abuse and severe sleep apnea and long respiratory events duration (200 and 275 seconds respectively) noted in polysomnography were reported at Ebn-e-Sina and Razavi hospita...
متن کاملDiagnosis of circadian rhythm sleep disorders.
Insomnia and excessive sleepiness are common in the investigation of sleep-disordered breathing. Circadian rhythm sleep disorders are perhaps the most often overlooked conditions in the differential diagnosis of these symptoms. Circadian rhythm sleep disorders manifest as misalignment between the sleep period and the physical/social 24-h environmental cycle. The two most prevalent circadian rhy...
متن کاملThe Cleveland adolescent sleepiness questionnaire: a new measure to assess excessive daytime sleepiness in adolescents.
STUDY OBJECTIVE Developed the Cleveland Adolescent Sleepiness Questionnaire (CASQ), a brief, self-completed instrument to measure excessive daytime sleepiness in adolescents. DESIGN Cross-sectional analysis. PARTICIPANTS A subsample of 411 adolescents 11-17 years of age recruited from area schools, churches, and "control" participants in a sleep disordered breathing cohort study; a second s...
متن کاملSymptom burden of sleep-disordered breathing in mild-to-moderate congestive heart failure patients.
The symptom burden resulting from sleep-disordered breathing (SDB) in patients with mild-to-moderate congestive heart failure (CHF) is unclear. The current authors monitored 24-h activity levels and compared subjective and objective measures of daytime sleepiness in 39 CHF patients, New York Heart Association class 2-3, on optimal medication. A total of 22 patients were classified as SDB (apnoe...
متن کامل